{"id":2479,"date":"2023-11-15T18:20:03","date_gmt":"2023-11-15T15:20:03","guid":{"rendered":"https:\/\/pharmaworlddergi.com\/?p=2479"},"modified":"2023-11-15T18:22:17","modified_gmt":"2023-11-15T15:22:17","slug":"koah-zaturre-gelisimi-icin-onemli-bir-risk-faktoru","status":"publish","type":"post","link":"https:\/\/pharmaworlddergi.com\/?p=2479","title":{"rendered":"KOAH Zat\u00fcrre Geli\u015fimi i\u00e7in \u00d6nemli Bir Risk Fakt\u00f6r\u00fc"},"content":{"rendered":"\n

Kronik obstr\u00fcktif akci\u011fer hastal\u0131\u011f\u0131 (KOAH), ba\u015fta t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri duman\u0131 olmak \u00fczere, zararl\u0131 toz, gaz ve par\u00e7ac\u0131klar\u0131n s\u00fcrekli solunmas\u0131 sonucunda geli\u015fen \u00f6nlenebilir ve tedavi edilebilir bir akci\u011fer hastal\u0131\u011f\u0131. KOAH hastalar\u0131nda ya\u015fam boyu genetik ve \u00e7evresel etkile\u015fimler sonucunda akci\u011ferde hasarlanma ve ya\u015flanma geli\u015fiyor.<\/strong> KOAH hastalar\u0131nda zat\u00fcrreye yakalanma olas\u0131l\u0131\u011f\u0131 sa\u011fl\u0131kl\u0131 topluma g\u00f6re yakla\u015f\u0131k 7-10 kat daha y\u00fcksek. T\u00fcrk Toraks Derne\u011fi Solunum Sistemi Enfeksiyonlar\u0131 \u00c7al\u0131\u015fma Grubu Y\u00fcr\u00fctme Kurulu \u00dcyesi Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu 16 Kas\u0131m D\u00fcnya KOAH G\u00fcn\u00fc vesilesiyle \u00f6nemli bilgiler payla\u015ft\u0131.<\/strong><\/p>\n\n\n

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Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong><\/figcaption><\/figure><\/div>\n\n\n

KOAH, ba\u015fta t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri (sigara, pipo, puro, nargile ve sarmal\u0131k \u00e7i\u011fnemelik t\u00fct\u00fcn, elektronik sigara, puflar) duman\u0131 olmak \u00fczere, zararl\u0131 toz, gaz ve par\u00e7ac\u0131klar\u0131n s\u00fcrekli solunmas\u0131 sonucunda geli\u015fen \u00f6nlenebilir ve tedavi edilebilir bir akci\u011fer hastal\u0131\u011f\u0131. Zararl\u0131 duman, gaz ve tozlara s\u00fcrekli maruz kalan akci\u011ferde solunan havay\u0131 ta\u015f\u0131yan havayollar\u0131 ve oksijen al\u0131\u015fveri\u015fini sa\u011flayan akci\u011fer dokusu olumsuz etkileniyor. Hava yollar\u0131nda geli\u015fen mikrobik olmayan iltihaplanma sonucu geri d\u00f6n\u00fc\u015f\u00fcms\u00fcz daralmalar geli\u015ferek solunan havan\u0131n akci\u011fer dokusuna iletilmesi engelleniyor. Benzer \u015fekilde solunan duman ve toz akci\u011fer dokusunda gaz al\u0131\u015fveri\u015fini sa\u011flayan hava keseciklerinde (alveol) geri d\u00f6n\u00fc\u015f\u00fcms\u00fcz harabiyet ve geni\u015flemelere sebep oluyor. Hastal\u0131\u011f\u0131n ileri d\u00f6nemlerinde solunum yetmezli\u011fine sebep oluyor.<\/p>\n\n\n\n

KOAH genel n\u00fcfusta olduk\u00e7a yayg\u0131nd\u0131r ve global olarak bu yayg\u0131nl\u0131k y\u00fczde 10,3 olarak bildirilmekte.<\/p>\n\n\n\n

D\u00fcnya KOAH G\u00fcn\u00fc 2023 temas\u0131 \u2018Nefes Hayatt\u0131r – Erken Harekete Ge\u00e7in\u2019<\/strong><\/p>\n\n\n\n

T\u00fcrk Toraks Derne\u011fi Solunum Sistemi Enfeksiyonlar\u0131 \u00c7al\u0131\u015fma Grubu Y\u00fcr\u00fctme Kurulu \u00dcyesi Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu:<\/strong> \u201cD\u00fcnya KOAH G\u00fcn\u00fc, Uluslararas\u0131 Solunum Topluluklar\u0131 Forumu’nun (FIRS) \u00fcyesi olan Kronik Obstr\u00fcktif Akci\u011fer Hastal\u0131\u011f\u0131 K\u00fcresel Giri\u015fimi (GOLD) taraf\u0131ndan y\u00fcr\u00fct\u00fclen y\u0131ll\u0131k k\u00fcresel bir giri\u015fimdir. D\u00fcnya KOAH G\u00fcn\u00fc’n\u00fcn amac\u0131 d\u00fcnya \u00e7ap\u0131nda KOAH konusunda fark\u0131ndal\u0131k yaratmak ve yeni bilgi ve yeni tedavi stratejileri sunmakt\u0131r. Bu y\u0131l 15 Kas\u0131m\u2019da ger\u00e7ekle\u015fecek \u201cD\u00fcnya KOAH G\u00fcn\u00fc 2023\u201d, “Nefes Hayatt\u0131r- Erken Harekete Ge\u00e7in” temas\u0131 ile erken tan\u0131 ve tedavinin KOAH seyrindeki \u00f6nemini vurgulamay\u0131 ama\u00e7lamaktad\u0131r\u201d dedi.<\/p>\n\n\n\n

KOAH\u2019a ait belirti ve bulgular 50\u2019li ya\u015flarda belirginle\u015fir<\/strong><\/p>\n\n\n\n

KOAH\u2019\u0131n belirtilerinin ve bulgular\u0131n\u0131n 50\u2019li ya\u015flarda belirginle\u015fmesinin ba\u015fl\u0131ca nedeninin kronik toz, duman maruziyetinin uzun y\u0131llar i\u00e7inde hasar geli\u015ftirmesidir diyen Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu <\/strong>s\u00f6zlerine \u015funlar\u0131 ekledi: \u201cGenel n\u00fcfusta olduk\u00e7a yayg\u0131n olan KOAH\u2019\u0131n, d\u00fcnya genelinde her y\u0131l \u00fc\u00e7 milyon ki\u015finin \u00f6l\u00fcm\u00fcne sebep oldu\u011fu tahmin edilmektedir. \u00d6l\u00fcmlerin y\u00fczde 90\u2019\u0131 d\u00fc\u015f\u00fck ve orta gelirli \u00fclkelerde ger\u00e7ekle\u015fmektedir. Bu say\u0131n\u0131n yaln\u0131zca ya\u015flanan d\u00fcnya n\u00fcfusu ve devam eden risk fakt\u00f6rlerine maruz kalma nedeniyle artmas\u0131 beklenmektedir. B\u00fcy\u00fck \u00f6l\u00e7ekli epidemiyolojik \u00e7al\u0131\u015fmalara dayanarak, bu oran \u00fclkelerin gelir d\u00fczeyine g\u00f6re de\u011fi\u015fkenlik g\u00f6stermekte olup, d\u00fc\u015f\u00fck ve orta gelirli \u00fclkelerde sigara i\u00e7imi, \u00e7evresel kirlilik nedeniyle daha y\u00fcksektir. Y\u00fcksek gelirli \u00fclkelerde ise ya\u015flanan n\u00fcfus nedeniyle KOAH yayg\u0131nl\u0131\u011f\u0131 artmaktad\u0131r.<\/p>\n\n\n\n

T.C. Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131 verilerine g\u00f6re; KOAH\u2019\u0131n 40 ya\u015f \u00fcst\u00fc yeti\u015fkinlerde g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131 y\u00fczde 15-20 olup, her 10 KOAH hastas\u0131ndan sadece biri doktora ba\u015fvurmakta ve do\u011fru tan\u0131 alabilmektedir. T\u00fcrkiye\u2019de bulunan yakla\u015f\u0131k 6 milyon KOAH\u2019l\u0131 bireyden sadece 400-600 bininin hastal\u0131k tan\u0131s\u0131na sahip oldu\u011fu bilinmektedir. T\u00fcrkiye\u2019de solunum sistemi hastal\u0131klar\u0131 en s\u0131k g\u00f6r\u00fclen \u00fc\u00e7\u00fcnc\u00fc \u00f6l\u00fcm nedenidir ve bu \u00f6l\u00fcmlerin de y\u00fczde 61,5\u2019i KOAH kaynakl\u0131d\u0131r.\u201d<\/p>\n\n\n\n

KOAH i\u00e7in bilinen en \u00f6nemli risk fakt\u00f6r\u00fc t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri kullan\u0131m\u0131d\u0131r<\/strong><\/p>\n\n\n\n

KOAH\u2019\u0131n yakla\u015f\u0131k olarak 20 y\u0131l boyunca g\u00fcnde bir paket sigara t\u00fcketimi sonras\u0131nda ortaya \u00e7\u0131kt\u0131\u011f\u0131n\u0131, e\u011fer g\u00fcnde bir paketten daha fazla say\u0131da sigara i\u00e7iliyorsa bu zaman\u0131n daha da k\u0131sald\u0131\u011f\u0131n\u0131 vurgulayan Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong>:\u201cKOAH tan\u0131s\u0131 alan ki\u015filerin b\u00fcy\u00fck \u00e7o\u011funlu\u011funda aktif ya da ge\u00e7mi\u015fte t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcn\u00fc kullan\u0131m \u00f6yk\u00fcs\u00fc vard\u0131r. Bu noktada, g\u00fcn\u00fcm\u00fczde kullan\u0131m\u0131 te\u015fvik edilen elektronik sigaralar\u0131n (puff) da akci\u011ferlere en az sigara kadar hasar verdi\u011fini vurgulamakta yarar var. Hastal\u0131k sinsi ilerledi\u011fi ve ortaya \u00e7\u0131kan \u00f6ks\u00fcr\u00fck, balgam \u00e7\u0131karma gibi \u015fikayetler genelde kullan\u0131lan t\u00fct\u00fcn \u00fcr\u00fcn\u00fc duman\u0131 ile ili\u015fkilendirildi\u011fi i\u00e7in bulgular \u00f6nemsenmez. KOAH te\u015fhisi gecikmeli olarak kondu\u011funda hastalar art\u0131k akci\u011fer kapasitelerinin \u00f6nemli bir k\u0131sm\u0131n\u0131 kaybetmi\u015f olurlar. T\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri d\u0131\u015f\u0131nda, i\u00e7 ortam hava kirlili\u011fi, \u00e7evresel ya da mesleki olarak \u00e7e\u015fitli gaz ve tozlara maruziyet ve hava kirlili\u011fi de KOAH geli\u015fimi i\u00e7in \u00f6nemli risk fakt\u00f6rlerindendir. Nadiren genetik (Kal\u0131tsal alfa-1 antitripsin eksikli\u011fi) ge\u00e7i\u015fle de KOAH geli\u015febilir\u201d dedi.<\/p>\n\n\n\n

KOAH hastal\u0131\u011f\u0131n\u0131n temel belirtileri nefes darl\u0131\u011f\u0131, \u00f6ks\u00fcr\u00fck ve balgamd\u0131r<\/strong><\/p>\n\n\n\n

Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong>: \u201cHastalar en fazla nefes darl\u0131\u011f\u0131, \u00f6ks\u00fcr\u00fck ve balgamdan yak\u0131n\u0131r. Kronik \u00f6ks\u00fcr\u00fck ve balgam \u00e7\u0131karma hastal\u0131\u011f\u0131n ba\u015flang\u0131\u00e7 bulgular\u0131d\u0131r ve \u00e7o\u011fu zaman g\u00f6z ard\u0131 edilir. Hastalar ancak nefes darl\u0131\u011f\u0131 belirgin hale geldi\u011finde doktora ba\u015fvurur. Bu yak\u0131nmalar, hastal\u0131k \u015fiddetinin artt\u0131\u011f\u0131 ve \u201calevlenme\u201d olarak adland\u0131r\u0131lan d\u00f6nemlerde daha da belirginle\u015fir ve hastaneye yat\u0131\u015f gerektirebilir. A\u011f\u0131r KOAH\u2019l\u0131 olgularda kan oksijen d\u00fczeyi d\u00fc\u015ft\u00fc\u011f\u00fc i\u00e7in bu olgular\u0131n hareket yetenekleri giderek azal\u0131r, istirahatte dahi nefes darl\u0131\u011f\u0131 geli\u015fir\u201d dedi.<\/p>\n\n\n\n

Sa\u011fl\u0131kl\u0131 akci\u011ferler i\u00e7in erken ya\u015ftan itibaren d\u00fczenli egzersiz \u00f6nem ta\u015f\u0131r<\/strong><\/p>\n\n\n\n

KOAH\u2019a kar\u015f\u0131 korunmada temel prensip KOAH\u2019a sebep olabilecek t\u00fcm unsurlara maruziyetten uzak durulmas\u0131d\u0131r uyar\u0131s\u0131nda bulunan Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong> s\u00f6zlerine \u015f\u00f6yle devam etti: \u201dHastal\u0131\u011f\u0131n en \u00f6nemli risk fakt\u00f6r\u00fc t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnlerinin kullan\u0131m\u0131 olmas\u0131 nedeniyle bu maddelerin kullan\u0131lmamas\u0131, kullan\u0131l\u0131yor ise de b\u0131rak\u0131lmas\u0131 hastal\u0131ktan korunabilmeyi m\u00fcmk\u00fcn k\u0131lmaktad\u0131r. \u00d6zellikle toz ve dumana maruz kal\u0131nan mesleklerde \u00e7al\u0131\u015fan ki\u015filerin t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri kullanmalar\u0131, KOAH\u2019a yakalanma riskini art\u0131raca\u011f\u0131ndan bu ki\u015filerin t\u00fcm t\u00fct\u00fcn \u00fcr\u00fcnlerinden uzak durmalar\u0131 daha fazla \u00f6nem kazanmaktad\u0131r. Ayr\u0131ca bu i\u015fyerlerinde, toz ve duman gibi maddelere maruz kalma derecesini azaltacak maske kullan\u0131m\u0131, uygun i\u015f yeri ortam\u0131n\u0131n sa\u011flanmas\u0131 gibi \u00f6nlemlerin al\u0131nmas\u0131 \u00f6nemlidir. Daha \u00e7ok k\u0131rsal kesimde evlerde yemek pi\u015firmek ya da \u0131s\u0131nmak amac\u0131yla kullan\u0131lan hayvansal ya da bitkisel kaynakl\u0131 yak\u0131tlar\u0131n yerine, ba\u015fka kaynaklar\u0131n kullan\u0131lmas\u0131 \u00f6nerilmektedir. Sa\u011fl\u0131kl\u0131 akci\u011ferler i\u00e7in erken ya\u015ftan itibaren d\u00fczenli egzersiz \u00f6nem ta\u015f\u0131r. \u00d6te yandan, KOAH hastalar\u0131nda solunum kapasitesinin giderek azalmas\u0131 nedeniyle bu hastalar\u0131n d\u00fczenli egzersizler yapmalar\u0131 solunum kapasitesinin korunmas\u0131 a\u00e7\u0131s\u0131ndan de\u011ferlidir.\u201d<\/p>\n\n\n\n

KOAH geli\u015fiminde \u00e7evresel ve genetik pek \u00e7ok fakt\u00f6r vard\u0131r<\/strong><\/p>\n\n\n\n

Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong>: \u201cKOAH hastalar\u0131nda ya\u015fam boyu genetik ve \u00e7evresel etkile\u015fimler sonucunda akci\u011ferde hasarlanma ve ya\u015flanma geli\u015fir. Ortaya \u00e7\u0131kan bu de\u011fi\u015fiklikler ilerleyicidir ve geri d\u00f6n\u00fc\u015f\u00fcm\u00fc s\u0131n\u0131rl\u0131d\u0131r. Bu nedenle, do\u011fumdan itibaren akci\u011fer sa\u011fl\u0131\u011f\u0131 ve \u00e7evresel etkenlerin izlenmesi, KOAH’\u0131n erken te\u015fhis edilmesi ve tedavinin derhal sa\u011flanmas\u0131 toplumun KOAH hastal\u0131k y\u00fck\u00fcn\u00fc azaltmak ve ya\u015fam kalitesini art\u0131rmak konusunda b\u00fcy\u00fck \u00f6nem ta\u015f\u0131maktad\u0131r. Bu kapsamda, sigara ve di\u011fer t\u00fct\u00fcn \u00fcr\u00fcnlerini b\u0131rakma programlar\u0131, i\u00e7 ve d\u0131\u015f mekan hava kirlili\u011fine kar\u015f\u0131 m\u00fccadelenin yan\u0131 s\u0131ra \u00e7ocukluktaki riskli durumlar\u0131n incelenmesine y\u00f6nelik planlamalar KOAH\u2018dan korunmada \u00f6nemlidir. \u00c7evresel etkenlerden uzak durmak, temiz hava solumak ve soludu\u011fumuz havay\u0131 temiz tutmak konusunda duyarl\u0131 olmam\u0131z\u0131n yan\u0131 s\u0131ra akci\u011fer sa\u011fl\u0131\u011f\u0131na y\u00f6nelik d\u00fczenli egzersizlere dikkat etmek hepimizin kolayl\u0131kla uygulayabilece\u011fi ve halk sa\u011fl\u0131\u011f\u0131 a\u00e7\u0131s\u0131ndan etkin \u00f6nlemlerdir. Ayr\u0131ca do\u011fumdan itibaren KOAH geli\u015fimini kolayla\u015ft\u0131ran yap\u0131sal de\u011fi\u015fiklilere sahip ki\u015filerde yak\u0131n takip hastal\u0131k y\u00fck\u00fcn\u00fc azaltmak a\u00e7\u0131s\u0131ndan \u00f6nemlidir. Her alevlenme KOAH hastal\u0131\u011f\u0131n\u0131 a\u011f\u0131rla\u015ft\u0131rabilece\u011fi i\u00e7in bu ki\u015filerin alevlenmelerden korunmas\u0131na y\u00f6nelik a\u015f\u0131lamalar yayg\u0131nla\u015fmal\u0131d\u0131r\u201d dedi.<\/p>\n\n\n\n

KOAH hastalar\u0131 a\u015f\u0131 ile zat\u00fcrreden korunabilir<\/strong><\/p>\n\n\n\n

KOAH hastalar\u0131nda akci\u011fer dokusunun iltihaplanmas\u0131 olarak tan\u0131mlanan zat\u00fcrre geli\u015fiminde en s\u0131k grip, RSV gibi vir\u00fcsler ya da pn\u00f6mokok gibi bakteriler sorumludur diyen Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu: <\/strong>\u201cZat\u00fcrre, KOAH hastal\u0131\u011f\u0131n\u0131 alevlendirerek solunum yetmezli\u011fi olas\u0131l\u0131\u011f\u0131n\u0131 art\u0131rarak v\u00fccudun oksijen alamamas\u0131na sebep olabilir. KOAH alevlenmeleri ve toplumda geli\u015fen zat\u00fcrrelerde sorumlu etkenler benzerdir. Bu nedenle hastalar\u0131n zat\u00fcrre, grip a\u015f\u0131lar\u0131n\u0131 yapt\u0131rmalar\u0131 onlar\u0131 alevlenmelerden ve zat\u00fcrre geli\u015fimden koruyacakt\u0131r. Elimizde bulunan 13 valanl\u0131 konjuge pn\u00f6mokok yani zat\u00fcrre a\u015f\u0131s\u0131 13 pn\u00f6mokok tipine kar\u015f\u0131 koruyucudur ve KOAH hastalar\u0131nda tek doz uygulanmaktad\u0131r. 23 valanl\u0131 polisakkarit a\u015f\u0131 da 23 pn\u00f6mokok tipine kar\u015f\u0131 koruyucudur. Bu a\u015f\u0131lar\u0131n bilinen hayati yan etkisi bulunmamaktad\u0131r. Grip a\u015f\u0131s\u0131n\u0131n ise i\u00e7eri\u011finin her y\u0131l yenilenmesi nedeniyle y\u0131ll\u0131k tekrarlanmas\u0131 uygundur. Risk grubu hastalar Aile Sa\u011fl\u0131k Merkezlerinde, eri\u015fkin a\u015f\u0131lama polikliniklerinde a\u015f\u0131lar\u0131n\u0131 rahatl\u0131kla yapt\u0131rabilirler. Re\u00e7ete edilen a\u015f\u0131lar eczanelerden temin edilebilmektedir\u201d dedi.<\/p>\n\n\n\n

Bireyler grip a\u015f\u0131s\u0131yla e\u015f zamanl\u0131 zat\u00fcrre a\u015f\u0131s\u0131 da yapt\u0131rabilirler<\/strong><\/p>\n\n\n\n

A\u015f\u0131lar aras\u0131 bir s\u00fcre olmas\u0131n\u0131n gerekli olmad\u0131\u011f\u0131n\u0131 ifade eden Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu<\/strong>, bireylerin grip a\u015f\u0131s\u0131yla e\u015f zamanl\u0131 zat\u00fcrre a\u015f\u0131s\u0131 da yapt\u0131rabilece\u011finin alt\u0131n\u0131 \u00e7izdi ve ekledi: \u201cHastal\u0131klar ile ba\u015f edebilmenin iki unsuru vard\u0131r. Birincisi hastal\u0131ktan korunmak, ikincisi ise do\u011fru tedaviyi uygulamak. A\u015f\u0131lar insanl\u0131k tarihinde bilinen en etkili, hastal\u0131ktan koruyucu temel t\u0131bbi uygulamalard\u0131r. A\u015f\u0131 olan ki\u015filer hastal\u0131\u011f\u0131 ge\u00e7irseler dahi a\u011f\u0131r hastal\u0131k, hastaneye yat\u0131\u015f ve \u00f6l\u00fcmlerden belirgin olarak korunurlar. Bu durum KOAH i\u00e7in de ge\u00e7erlidir. Zat\u00fcrre a\u015f\u0131s\u0131 olmu\u015f KOAH hastalar\u0131nda zat\u00fcrre ya da alevlenme geli\u015fme olas\u0131l\u0131\u011f\u0131 anlaml\u0131 d\u00fczeyde d\u00fc\u015fmektedir.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

Kronik obstr\u00fcktif akci\u011fer hastal\u0131\u011f\u0131 (KOAH), ba\u015fta t\u00fct\u00fcn ve t\u00fct\u00fcn \u00fcr\u00fcnleri duman\u0131 olmak \u00fczere, zararl\u0131 toz, gaz ve par\u00e7ac\u0131klar\u0131n s\u00fcrekli solunmas\u0131 sonucunda geli\u015fen \u00f6nlenebilir ve tedavi edilebilir bir akci\u011fer hastal\u0131\u011f\u0131. KOAH hastalar\u0131nda ya\u015fam boyu genetik ve \u00e7evresel etkile\u015fimler sonucunda akci\u011ferde hasarlanma ve ya\u015flanma geli\u015fiyor. KOAH hastalar\u0131nda zat\u00fcrreye yakalanma olas\u0131l\u0131\u011f\u0131 sa\u011fl\u0131kl\u0131 topluma g\u00f6re yakla\u015f\u0131k 7-10 kat daha y\u00fcksek. T\u00fcrk Toraks Derne\u011fi Solunum Sistemi Enfeksiyonlar\u0131 \u00c7al\u0131\u015fma Grubu Y\u00fcr\u00fctme Kurulu \u00dcyesi Prof. Dr. F\u00fcsun \u00d6ner Ey\u00fcbo\u011flu 16 Kas\u0131m D\u00fcnya KOAH G\u00fcn\u00fc vesilesiyle \u00f6nemli bilgiler payla\u015ft\u0131.<\/p>\n","protected":false},"author":1,"featured_media":2480,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[48,3],"tags":[126],"_links":{"self":[{"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/posts\/2479"}],"collection":[{"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2479"}],"version-history":[{"count":2,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/posts\/2479\/revisions"}],"predecessor-version":[{"id":2483,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/posts\/2479\/revisions\/2483"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=\/wp\/v2\/media\/2480"}],"wp:attachment":[{"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2479"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2479"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmaworlddergi.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}